Combination of Sambiloto & Herbal, Immunomodulator for Body Endurance

celepeng342
4 min readFeb 3, 2021

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The COVID-19 pandemic in Indonesia has not shown any signs of abating soon. For this reason, people need to always be disciplined in implementing preventive protocols, pursuing healthy habits, and maintaining body immunity, one of which is by using herbal medicines.
Dr. Rianti Maharani from the Indonesian Herbal Medicine Doctors Association (PDHMI) explained that COVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2).

The COVID-19 virus is so contagious that it requires discipline from all parties to undergo prevention protocols. This virus can be transmitted through SAR-CoV-2 direct contact with patients, droplets released by sufferers when coughing or sneezing, and hands touching the mouth, nose and eyes after touching objects contaminated with these viruses.
Therefore, COVID-19 is also known as a thousand faces disease. Because this virus can cause various kinds of symptoms. Such as fever, headache, muscle aches, smell disturbances, decreased taste, sore throat, cough, respiratory problems, nausea, vomiting and abdominal pain. There is also a COVID-19 infection that is asymptomatic and more difficult to detect.
To prevent transmission of COVID-19, the community needs to strive for health resilience that depends on the health of the individual body. It is also important to maintain endurance by adopting healthy habits and using traditional medicines that can increase immunity.

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The human immune system consists of the innate immune system and the adaptive immune system. To be able to activate natural and adaptive defense mechanisms,
Sambiloto, The King of Bitter Disease

Sambiloto (Andrographis Paniculata), better known as Raja Pahit, or if in the Java area is known for making paitan stew, has many properties that have been proven empirically and scientifically. Empirically, sambiloto is traditionally used to increase endurance, anti-diarrhea, liver disorders, and anti-bacterial. Meanwhile, based on scientific evidence, Sambiloto has been studied to successfully increase endurance, lower cholesterol, have anti-diabetic, anti-diarrheal, anti-fever, anti-fertility, liver disorders and anti-bacterial activities.

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As an antiviral, sambiloto can increase the phagocytosis activity of lymphocytes which can control the virus. Not only that, bitter also plays a role in immunostimulants. The andrographolide content in sambiloto can prevent virus transmission to other cells and stop disease progression by modifying reduced cellular signals. Andrographolid is the main active component in the herb sambiloto.
Other pharmacological activities include immunosuppressants, antithrombotic, antiviral, antioxidant and anti-inflammatory properties. Andrographolid as anti-inflammatory and antioxidant works against various body cells with specific mechanisms. Other studies have also shown that giving andrographolid to animals can stimulate antibody production.

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Herbal Combinations

The combination of red ginger, sembung, meniran and sambiloto as an innovative herbal immunomodulator synergizes in immunity protection. Some herbs that have immunomodulatory properties when combined in one preparation will work together to increase body immunity. Among them is a combination of red ginger, sembung, meniran and sambiloto.

The combination of the four native Indonesian herbs serves to restore the immune response, suppress inflammation, and fight viral infections. However, it is important to note that the public is advised to be able to maintain endurance in pandemic conditions like this by consuming balanced immunomodulators. Both of its function as immunostimulants and immunosuppressants.
Immunosuppressants are substances that stimulate the immune system by increasing the activity of the components of the immune system to fight infection and disease. Meanwhile, immunosuppressants are substances that can suppress excessive immune responses. Therefore, a balance is needed, namely the use of adequate immunostimulants and immunosuppressants. That way, the immunomodulators that are consumed will not cause side effects even if they are eaten regularly in the long term.

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You can get a series of health benefits from Sambiloto and synergy with three other herbs in Fatigon Promuno. Fatigon Promuno is an innovative herbal immunomodulator with four original herbs, namely sambiloto, red ginger, sembung, and meniran. The combination of the four native Indonesian herbs will help restore the immune response, suppress inflammation, and fight viral infections. Through 3 actions to maintain body immunity, Fatigon Promuno effectively optimizes endurance every day, especially during a pandemic.

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